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Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter

A significant volume of clinical and epidemiological data provides support to the concept that insulin and the insulin receptor (INSR) have an important role in breast cancer. Tumor suppressor p53 is the most frequently mutated molecule in human cancer. The present study was aimed at evaluating the...

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Pubblicato in:Oncotarget
Autori principali: Sarfstein, Rive, Werner, Haim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321701/
https://ncbi.nlm.nih.gov/pubmed/32637033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27645
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