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Bioengineering of Cytochrome P450 OleT(JE): How Does Substrate Positioning Affect the Product Distributions?

The cytochromes P450 are versatile enzymes found in all forms of life. Most P450s use dioxygen on a heme center to activate substrates, but one class of P450s utilizes hydrogen peroxide instead. Within the class of P450 peroxygenases, the P450 OleT(JE) isozyme binds fatty acid substrates and convert...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cantú Reinhard, Fabián G., Lin, Yen-Ting, Stańczak, Agnieszka, de Visser, Sam P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321372/
https://ncbi.nlm.nih.gov/pubmed/32526971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25112675
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