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Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies

Genome-wide association studies have led to a significant progress in identification of genomic loci affecting coronary artery disease (CAD) risk. However, revealing the causal genes responsible for the observed associations is challenging. In the present study, we aimed to prioritize CAD-relevant g...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Shadrina, Alexandra S., Shashkova, Tatiana I., Torgasheva, Anna A., Sharapov, Sodbo Z., Klarić, Lucija, Pakhomov, Eugene D., Alexeev, Dmitry G., Wilson, James F., Tsepilov, Yakov A., Joshi, Peter K., Aulchenko, Yurii S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320185/
https://ncbi.nlm.nih.gov/pubmed/32591598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67001-w
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