PD-1/PD-L1 expression and tumor-infiltrating lymphocytes are prognostically favorable in advanced high-grade serous ovarian carcinoma

The response rate to checkpoint inhibitors for women with high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum (HGSC) is modest, and development of predictive biomarkers is needed. The main focus has been on tumor cell PD-L1 expression, but its assessment alone is insufficient fo...

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Publicado en:Virchows Arch
Autores principales: Martin de la Fuente, Laura, Westbom-Fremer, Sofia, Arildsen, Nicolai Skovbjerg, Hartman, Linda, Malander, Susanne, Kannisto, Päivi, Måsbäck, Anna, Hedenfalk, Ingrid
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320055/
https://ncbi.nlm.nih.gov/pubmed/31980961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-020-02751-6
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