Effect of donor age and 3D-cultivation on osteogenic differentiation capacity of adipose-derived mesenchymal stem cells

Background and Purpose: Age and co-morbidities compromise healing tendencies of traumatic fractures in geriatric patients. Non-healing fractures may need regenerative medicine techniques involving autologous mesenchymal stem cells (MSCs). Donor age may affect the viability and differentiation capaci...

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Published in:Sci Rep
Main Authors: Payr, Stephan, Schuseil, Tim, Unger, Marina, Seeliger, Claudine, Tiefenboeck, Thomas, Balmayor, Elizabeth R., Griensven, Martijn van
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319953/
https://ncbi.nlm.nih.gov/pubmed/32591595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67254-5
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