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Cell organelle targeting of near-infrared croconaine dye controls photothermal outcome

Near-infrared croconaine-peptide conjugates that target the cell nucleus promote photothermal induced cell death. In contrast, a croconaine-morpholine conjugate that targets the cell lysosomes promotes lysosome permeabilization without measurable cell phototoxicity.

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Wen, Ying, McGarraugh, Hannah H., Schreiber, Cynthia L., Smith, Bradley D.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319869/
https://ncbi.nlm.nih.gov/pubmed/32436506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc02612c
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