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Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections
Ebselen is an organoselenium compound exhibiting hydroperoxide- and peroxynitrite-reducing activity, acting as a glutathione peroxidase and peroxiredoxin enzyme mimetic. Ebselen reacts with a multitude of protein thiols, forming a selenosulfide bond, which results in pleiotropic effects of antiviral...
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| Publicado en: | Free Radic Biol Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319625/ https://ncbi.nlm.nih.gov/pubmed/32598985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.06.032 |
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