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Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing
Base editing is a genome-editing approach that employs the CRISPR/Cas system to precisely install point mutations within the genome. A deaminase enzyme is fused to a deactivated Cas and enables transition conversions. The diversified repertoire of base editors provides a wide range of base editing p...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319459/ https://ncbi.nlm.nih.gov/pubmed/32255179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa215 |
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