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Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction

AIMS: Following a favourable pilot trial using a single bolus of ciclosporin, it has been unclear why 2 large studies (CYCLE and CIRCUS) failed to prevent reperfusion injury and reduce infarct size in STEMI (ST elevation myocardial infarction). The purpose of this study was to assess the effect of c...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Cormack, Suzanne, Mohammed, Ashfaq, Panahi, Pedram, Das, Rajiv, Steel, Alison J., Chadwick, Thomas, Bryant, Andrew, Egred, Mohaned, Stellos, Konstantinos, Spyridopoulos, Ioakim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318996/
https://ncbi.nlm.nih.gov/pubmed/32067256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14252
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