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The whole‐cell Ca(2+) release‐activated Ca(2+) current, I (CRAC), is regulated by the mitochondrial Ca(2+) uniporter channel and is independent of extracellular and cytosolic Na(+)
KEY POINTS: Ca(2+) entry through Ca(2+) release‐activated Ca(2+) channels activates numerous cellular responses. Under physiological conditions of weak intracellular Ca(2+) buffering, mitochondrial Ca(2+) uptake regulates CRAC channel activity. Knockdown of the mitochondrial Ca(2+) uniporter channel...
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| Pubblicato in: | J Physiol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318671/ https://ncbi.nlm.nih.gov/pubmed/30582626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276551 |
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