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Lung delivery of MSCs expressing anti-cancer protein TRAIL visualised with (89)Zr-oxine PET-CT

BACKGROUND: MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in mind, delivery is rarely assessed due to a lack of transla...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Patrick, P. Stephen, Kolluri, Krishna K., Zaw Thin, May, Edwards, Adam, Sage, Elizabeth K., Sanderson, Tom, Weil, Benjamin D., Dickson, John C., Lythgoe, Mark F., Lowdell, Mark, Janes, Sam M., Kalber, Tammy L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318529/
https://ncbi.nlm.nih.gov/pubmed/32586403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01770-z
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