Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis

BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD), an autoimmune astrocytopathic disease associated with the anti-aquaporin-4 (AQP4) antibody, is characterized by extensive necrotic lesions primarily located on the optic nerves and spinal cord. Tanshinone IIA (TSA), an active natural compou...

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Detalles Bibliográficos
Publicado en:J Neuroinflammation
Main Authors: Gong, Ye, Zhang, Ya-ling, Wang, Zhen, Song, Huan-huan, Liu, Yuan-chu, Lv, Ao-wei, Tian, Li-li, Zhu, Wen-li, Fu, Ying, Ding, Xiao-li, Cui, Lang-jun, Yan, Ya-ping
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318433/
https://ncbi.nlm.nih.gov/pubmed/32586353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01874-6
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