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Nonclinical safety assessment of repeated administration and biodistribution of ChAd3‐EBO‐Z Ebola candidate vaccine

ChAd3‐EBO‐Z is an investigational adenovirus‐based vaccine for the prevention of Ebola virus disease. Two nonclinical studies were performed to evaluate the biodistribution, local tolerance and potential local and systemic toxic effects of this vaccine. In the biodistribution study, rats received a...

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Detalhes bibliográficos
Publicado no:J Appl Toxicol
Main Authors: Planty, Camille, Chevalier, Guillaume, Duclos, Marie‐Ève, Chalmey, Clémentine, Thirion‐Delalande, Catherine, Sobry, Cécile, Steff, Ann‐Muriel, Destexhe, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318182/
https://ncbi.nlm.nih.gov/pubmed/31965598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3941
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