Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

[Image: see text] Off-target effects continue to impede disease interventions, particularly when targeting a specific protein within a family of similar proteins, such as kinase isoforms that play tumor-subtype-specific roles in cancers. Exploiting the specific electrophilic-metabolite-sensing capab...

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Publicat a:ACS Cent Sci
Autors principals: Liu, Xuyu, Long, Marcus J. C., Hopkins, Benjamin D., Luo, Chaosheng, Wang, Lingxi, Aye, Yimon
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318068/
https://ncbi.nlm.nih.gov/pubmed/32607436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00893
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