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Anidulafungin and Micafungin Concentrations in Cerebrospinal Fluid and in Cerebral Cortex

Anidulafungin and micafungin were quantified in cerebrospinal fluid (CSF) of critically ill adults and in cerebral cortex of deceased patients. In CSF, anidulafungin levels (<0.01 to 0.66 μg/ml) and micafungin levels (<0.01 to 0.16 μg/ml) were lower than those in plasma concentrations (0.77 to...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Marx, Jana, Welte, René, Gasperetti, Tiziana, Moser, Patrizia, Beer, Ronny, Ortler, Martin, Jeske, Martina, Stern, Ramona, Pomaroli, Andreas, Joannidis, Michael, Bellmann, Romuald
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318006/
https://ncbi.nlm.nih.gov/pubmed/32340985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00275-20
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