Influence of CYP2C8, CYP3A4, and CYP3A5 Host Genotypes on Early Recurrence of Plasmodium vivax

Cytochrome P450 (CYP) enzymes are involved in the biotransformation of chloroquine (CQ), but the role of the different profiles of metabolism of this drug in relation to Plasmodium vivax recurrences has not been properly investigated. To investigate the influence of the CYP genotypes associated with...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Almeida, Anne C. G., Puça, Maria C. B., Figueiredo, Erick F. G., Barbosa, Laila R., Salazar, Yanka E. A. R., Silva, Emanuelle L., Brito, Marcelo A. M., Siqueira, André M., Vieira, José L. F., Lacerda, Marcus V. G., Monteiro, Wuelton M., Melo, Gisely C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317997/
https://ncbi.nlm.nih.gov/pubmed/32366712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02125-19
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