Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

BACKGROUND AND AIMS: Monoacylglycerol lipase (MGL) is the last enzymatic step in triglyceride degradation, hydrolyzing monoglycerides into glycerol and fatty acids (FAs) and converting 2‐arachidonoylglycerol into arachidonic acid, thus providing ligands for nuclear receptors as key regulators of hep...

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Publicado no:Hepatology
Main Authors: Tardelli, Matteo, Bruschi, Francesca V., Fuchs, Claudia D., Claudel, Thierry, Auer, Nicole, Kunczer, Victoria, Baumgartner, Maximilian, A.H.O. Ronda, Onne, Verkade, Henk Jan, Stojakovic, Tatjana, Scharnagl, Hubert, Habib, Aida, Zimmermann, Robert, Lotersztajn, Sophie, Trauner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317927/
https://ncbi.nlm.nih.gov/pubmed/31505038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30929
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