Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

BACKGROUND AND AIMS: Monoacylglycerol lipase (MGL) is the last enzymatic step in triglyceride degradation, hydrolyzing monoglycerides into glycerol and fatty acids (FAs) and converting 2‐arachidonoylglycerol into arachidonic acid, thus providing ligands for nuclear receptors as key regulators of hep...

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Detalles Bibliográficos
Publicado en:Hepatology
Main Authors: Tardelli, Matteo, Bruschi, Francesca V., Fuchs, Claudia D., Claudel, Thierry, Auer, Nicole, Kunczer, Victoria, Baumgartner, Maximilian, A.H.O. Ronda, Onne, Verkade, Henk Jan, Stojakovic, Tatjana, Scharnagl, Hubert, Habib, Aida, Zimmermann, Robert, Lotersztajn, Sophie, Trauner, Michael
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317927/
https://ncbi.nlm.nih.gov/pubmed/31505038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30929
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