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Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.

BACKGROUND: Subcellular localization and function of L-type calcium channels (LTCCs) play an important role in regulating contraction of cardiomyocytes. Understanding how this is affected by the disruption of transverse tubules during heart failure could lead to new insights into the disease. METHOD...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Sanchez-Alonso, Jose L., Loucks, Alexandra, Schobesberger, Sophie, van Cromvoirt, Ankie M., Poulet, Claire, Chowdhury, Rasheda A., Trayanova, Natalia, Gorelik, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317229/
https://ncbi.nlm.nih.gov/pubmed/32580140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102845
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