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PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E(2)-Mediated Inhibition of IgE Production in Asthma
Increased serum IgE level is one of the features of allergic asthma. It is reported that IgE production can be enhanced by E-prostanoid 2 (EP2) receptor of prostaglandin E(2) (PGE(2)); however, whether E-prostanoid 4 (EP4) receptor (encoded by Ptger4) has a unique or redundant role is still unclear....
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317005/ https://ncbi.nlm.nih.gov/pubmed/32636842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01224 |
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