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The genetic architecture of Stargardt macular dystrophy (STGD1): a longitudinal 40-year study in a genetic isolate

Stargardt disease (STGD1) is a form of inherited retinal dystrophy attributed to variants affecting function of the large ABCA4 gene and is arguably the most complex monogenic disease. Therapeutic trials in patients depend on identifying causal ABCA4 variants in trans, which is complicated by extrem...

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Bibliografski detalji
Izdano u:Eur J Hum Genet
Glavni autori: Green, Jane S., O’Rielly, Darren D., Pater, Justin A., Houston, Jim, Rajabi, Hoda, Galutira, Dante, Benteau, Tammy, Sheaves, Amy, Abdelfatah, Nelly, Bautista, Donna, Whelan, Jim, Young, Terry-Lynn
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316815/
https://ncbi.nlm.nih.gov/pubmed/32467599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0581-4
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