Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss

Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle beyond the inherent regenerative capacity of the body, generally leading to severe functional deficit. Formation of appropriate somato-motor innervations remains one of the biggest challenges for both autologous grafts...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Das, Suradip, Browne, Kevin D., Laimo, Franco A., Maggiore, Joseph C., Hilman, Melanie C., Kaisaier, Halimulati, Aguilar, Carlos A., Ali, Zarina S., Mourkioti, Foteini, Cullen, D. Kacy
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316777/
https://ncbi.nlm.nih.gov/pubmed/32587337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1056-4
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