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Prediction of disulfide bond engineering sites using a machine learning method

Disulfide bonds are covalently bonded sulfur atoms from cysteine pairs in protein structures. Due to the importance of disulfide bonds in protein folding and structural stability, artificial disulfide bonds are often engineered by cysteine mutation to enhance protein structural stability. To facilit...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Gao, Xiang, Dong, Xiaoqun, Li, Xuanxuan, Liu, Zhijie, Liu, Haiguang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316719/
https://ncbi.nlm.nih.gov/pubmed/32587353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67230-z
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