Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

Plasmodium parasite-specific antibodies are critical for protection against malaria, yet the development of long-lived and effective humoral immunity against Plasmodium takes many years and multiple rounds of infection and cure. Here we report that the rapid development of short-lived plasmablasts d...

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發表在:Nat Immunol
Main Authors: Vijay, Rahul, Guthmiller, Jenna J., Sturtz, Alexandria J., Surette, Fionna A., Rogers, Kai J., Sompallae, Ramakrishna R., Li, Fengyin, Pope, Rosemary L., Chan, Jo-Anne, de Labastida Rivera, Fabian, Andrew, Dean, Webb, Lachlan, Maury, Wendy J., Xue, Hai-Hui, Engwerda, Christian R., McCarthy, James S., Boyle, Michelle J., Butler, Noah S.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316608/
https://ncbi.nlm.nih.gov/pubmed/32424361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0678-5
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