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Candida albicans Genetic Background Influences Mean and Heterogeneity of Drug Responses and Genome Stability during Evolution in Fluconazole

The importance of within-species diversity in determining the evolutionary potential of a population to evolve drug resistance or tolerance is not well understood, including in eukaryotic pathogens. To examine the influence of genetic background, we evolved replicates of 20 different clinical isolat...

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Publicado en:mSphere
Main Authors: Gerstein, Aleeza C., Berman, Judith
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316494/
https://ncbi.nlm.nih.gov/pubmed/32581072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00480-20
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