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Trastuzumab effects depend on HER2 phosphorylation in HER2-negative breast cancer cell lines
The breast cancer (BC) biomarker HER2 (Human Epidermal Receptor 2) is overexpressed in 25% of BC. Only patients with HER2-positive tumors receive HER2-targeting therapies, like trastuzumab (Herceptin). However, some women with a HER2-negative BC could benefit from trastuzumab. This could be explaine...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316326/ https://ncbi.nlm.nih.gov/pubmed/32584853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234991 |
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