Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis

Programmed axonal degeneration, also known as Wallerian degeneration, occurs in immune-mediated central nervous system (CNS) inflammatory disorders such as multiple sclerosis and the animal model experimental allergic encephalomyelitis (EAE). Sterile alpha and TIR domain containing protein 1 (SARM1)...

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Bibliographic Details
Published in:PLoS One
Main Authors: Viar, Kenneth, Njoku, Daniel, Secor McVoy, Julie, Oh, Unsong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316289/
https://ncbi.nlm.nih.gov/pubmed/32584865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235110
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