Inferring the molecular mechanisms of noncoding Alzheimer’s disease-associated genetic variants

More than 20 genetic variants associated with late-onset Alzheimer’s disease (LOAD) have been identified by genome-wide association studies (GWAS). However, these variants are tag markers for nearby genetic variants in linkage disequilibrium (LD) and may not be themselves functional. Moreover, most...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Amlie-Wolf, Alexandre, Tang, Mitchell, Way, Jessica, Dombroski, Beth, Jiang, Ming, Vrettos, Nicholas, Chou, Yi-Fan, Zhao, Yi, Kuzma, Amanda, Mlynarski, Elisabeth E., Leung, Yuk Yee, Brown, Christopher D., Wang, Li-San, Schellenberg, Gerard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316086/
https://ncbi.nlm.nih.gov/pubmed/31561366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190568
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