Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

BACKGROUND: Hispanic/Latino (HL) populations bear a disproportionately high burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk scores (PRS) offers great promise for improved screening and prevention. However, there are a number of complications related to t...

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Udgivet i:BMC Med Genet
Main Authors: Chande, Aroon T., Rishishwar, Lavanya, Conley, Andrew B., Valderrama-Aguirre, Augusto, Medina-Rivas, Miguel A., Jordan, I. King
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
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Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315475/
https://ncbi.nlm.nih.gov/pubmed/32580712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01068-0
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