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Exceptional nuclease resistance of paranemic crossover (PX) DNA and crossover-dependent biostability of DNA motifs

Nanometer-sized features and molecular recognition properties make DNA a useful material for nanoscale construction, but degradation in biological fluids poses a considerable roadblock to biomedical applications of DNA nanotechnology. Here we report the remarkable biostability of a multi-stranded mo...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Chandrasekaran, Arun Richard, Vilcapoma, Javier, Dey, Paromita, Wong-Deyrup, Siu Wah, Dey, Bijan K., Halvorsen, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315441/
https://ncbi.nlm.nih.gov/pubmed/32208657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c02211
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