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Protein Binding Pocket Optimization for Virtual High-Throughput Screening (vHTS) Drug Discovery

[Image: see text] The virtual high-throughput screening (vHTS) approach has been widely used for large database screening to identify potential lead compounds for drug discovery. Due to its high computational demands, docking that allows receptor flexibility has been a challenging problem for virtua...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:ACS Omega
Main Authors: Gazgalis, Dimitris, Zaka, Mehreen, Abbasi, Bilal Haider, Logothetis, Diomedes E., Mezei, Mihaly, Cui, Meng
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2020
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315428/
https://ncbi.nlm.nih.gov/pubmed/32596567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00522
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