In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium-Handling Machinery and Cardiac Function

Heart failure is an important, and growing, cause of morbidity and mortality. Half of patients with heart failure have preserved ejection fraction, for whom therapeutic options are limited. Here we report that cardiac bridging integrator 1 gene therapy to maintain subcellular membrane compartments w...

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Publicat a:JACC Basic Transl Sci
Autors principals: Liu, Yan, Zhou, Kang, Li, Jing, Agvanian, Sosse, Caldaruse, Ana-Maria, Shaw, Seiji, Hitzeman, Tara C., Shaw, Robin M., Hong, TingTing
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
PRECLINICAL RESEARCH
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315191/
https://ncbi.nlm.nih.gov/pubmed/32613144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.03.006
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