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Role of the Extracellular Matrix in Loss of Muscle Force With Age and Unloading Using Magnetic Resonance Imaging, Biochemical Analysis, and Computational Models

The focus of this review is the application of advanced MRI to study the effect of aging and disuse related remodeling of the extracellular matrix (ECM) on force transmission in the human musculoskeletal system. Structural MRI includes (i) ultra-low echo times (UTE) maps to visualize and quantify th...

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Pubblicato in:Front Physiol
Autori principali: Sinha, Usha, Malis, Vadim, Chen, Jiun-Shyan, Csapo, Robert, Kinugasa, Ryuta, Narici, Marco Vincenzo, Sinha, Shantanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315044/
https://ncbi.nlm.nih.gov/pubmed/32625114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00626
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