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Farnesoid X receptor activation inhibits TGFBR1/TAK1-mediated vascular inflammation and calcification via miR-135a-5p

Chronic inflammation plays a crucial role in vascular calcification. However, only a few studies have revealed the mechanisms underlying the development of inflammation under high-phosphate conditions in chronic kidney disease (CKD) patients. Here, we show that inflammation resulting from the activa...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Li, Chao, Zhang, Shijun, Chen, Xiaoqing, Ji, Jingkang, Yang, Wenqing, Gui, Ting, Gai, Zhibo, Li, Yunlun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314757/
https://ncbi.nlm.nih.gov/pubmed/32581266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1058-2
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