Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae

The extent to which evolution is constrained by the rate at which horizontal gene transfer (HGT) allows DNA to move between genetic lineages is an open question, which we address in the context of antibiotic resistance in Streptococcus pneumoniae. We analyze microbiological, genomic, and epidemiolog...

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Vydáno v:Sci Adv
Hlavní autoři: Lehtinen, Sonja, Chewapreecha, Claire, Lees, John, Hanage, William P., Lipsitch, Marc, Croucher, Nicholas J., Bentley, Stephen D., Turner, Paul, Fraser, Christophe, Mostowy, Rafał J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314567/
https://ncbi.nlm.nih.gov/pubmed/32671212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6137
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