Remote modulation of lncRNA GCLET by risk variant at 16p13 underlying genetic susceptibility to gastric cancer

The biological effects of susceptibility loci are rarely reported in gastric tumorigenesis. We conducted a large-scale cross-ancestry genetic study in 18,852 individuals and identified the potential causal variant rs3850997 T>G at 16p13 significantly associated with a decreased risk of gastric ca...

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Pubblicato in:Sci Adv
Autori principali: Du, Mulong, Zheng, Rui, Ma, Gaoxiang, Chu, Haiyan, Lu, Jiafei, Li, Shuwei, Xin, Junyi, Tong, Na, Zhang, Gang, Wang, Weizhi, Qiang, Fulin, Gong, Weida, Zhao, Qinghong, Tao, Guoquan, Chen, Jinfei, Jia, Zhifang, Jiang, Jing, Jin, Guangfu, Hu, Zhibin, Shen, Hongbing, Wang, Meilin, Zhang, Zhengdong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314563/
https://ncbi.nlm.nih.gov/pubmed/32671202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5525
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