Inhibitory Parvalbumin Basket Cell Activity is Selectively Reduced during Hippocampal Sharp Wave Ripples in a Mouse Model of Familial Alzheimer's Disease

Memory disruption in mild cognitive impairment (MCI) and Alzheimer's disease (AD) is poorly understood, particularly at early stages preceding neurodegeneration. In mouse models of AD, there are disruptions to sharp wave ripples (SWRs), hippocampal population events with a critical role in memo...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Caccavano, Adam, Bozzelli, P. Lorenzo, Forcelli, Patrick A., Pak, Daniel T.S., Wu, Jian-Young, Conant, Katherine, Vicini, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314414/
https://ncbi.nlm.nih.gov/pubmed/32439703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0425-20.2020
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