Astragaloside IV attenuates high glucose-induced EMT by inhibiting the TGF-β/Smad pathway in renal proximal tubular epithelial cells

In the present study, we examined the molecular mechanism of astragaloside IV (AS-IV) in high glucose (HG)-induced epithelial-to-mesenchymal transition (EMT) in renal proximal tubular epithelial cells (PTCs). NRK-52E cell viability and apoptosis were determined by the cell counting kit-8 (CCK-8) ass...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Wang, Ya-Ning, Zhao, Shi-Li, Su, Yan-Yan, Feng, Jun-Xia, Wang, Shuai, Liao, Xiao-Ming, Wang, Li-Na, Li, Jing-Chun, Meng, Ping, Li, Hong-Yan, Zhang, Yun-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Diabetes & Metabolic Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313447/
https://ncbi.nlm.nih.gov/pubmed/32515466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190987
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