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Occupation of a thermoresistant-scaffold (αRep) at SP1-NC cleavage site disturbs the function of HIV-1 protease

HIV-1 nucleocapsid (NC) becomes an attractive target for the development of novel anti-HIV-1 agents. Discovering of non-antibody scaffolds that disrupt the function of NC will be a potential aspect for disturbing viral maturation process. Correspondingly, we explored the specific binding site of the...

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Foilsithe in:Biosci Rep
Main Authors: Hadpech, Sudarat, Peerakam, Nichakan, Chupradit, Koollawat, Tayapiwatana, Chatchai
Formáid: Artigo
Teanga:Inglês
Foilsithe: Portland Press Ltd. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313444/
https://ncbi.nlm.nih.gov/pubmed/32519747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201131
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