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HSP70-Mediated NLRP3 Inflammasome Suppression Underlies Reversal of Acute Kidney Injury Following Extracellular Vesicle and Focused Ultrasound Combination Therapy

Acute kidney injury (AKI) is the abrupt loss of renal function, for which only supportive therapies exist. Mesenchymal stromal cell (MSC)-derived extracellular vesicles (EVs) have been shown to be therapeutically effective in treating AKI by spurring endogenous cell proliferation and survival while...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ullah, Mujib, Liu, Daniel D., Rai, Sravanthi, Concepcion, Waldo, Thakor, Avnesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312940/
https://ncbi.nlm.nih.gov/pubmed/32521623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114085
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