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The Central Kink Region of Fowlicidin-2, an α-Helical Host Defense Peptide, Is Critically Involved in Bacterial Killing and Endotoxin Neutralization

Fowlicidins are a group of newly identified chicken cathelicidin host defense peptides. We have shown that the putatively mature fowlicidin-2 of 31 amino acid residues possesses potent antibacterial and lipopolysaccharide (LPS)- neutralizing activities, but with a noticeable toxicity to mammalian ce...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Xiao, Yanjing, Herrera, Alvaro I., Bommineni, Yugendar R., Soulages, Jose L., Prakash, Om, Zhang, Guolong
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312843/
https://ncbi.nlm.nih.gov/pubmed/20375584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000174822
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