A New Pathway of Staphylococcal Pathogenesis: Apoptosis-Like Death Induced by Staphopain B in Human Neutrophils and Monocytes

Circulating neutrophils and monocytes form the first line of cellular defense against invading bacteria. Here, we describe a novel and specific mechanism of disabling and eliminating phagocytes by Staphylococcus aureus. Staphopain B (SspB) selectively cleaved CD11b on phagocytes, which rapidly acqui...

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Библиографические подробности
Опубликовано в: :J Innate Immun
Главные авторы: Smagur, Jan, Guzik, Krzysztof, Magiera, Lukasz, Bzowska, Malgorzata, Gruca, Milosz, Thøgersen, Ida B., Enghild, Jan J., Potempa, Jan
Формат: Artigo
Язык:Inglês
Опубликовано: S. Karger AG 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312767/
https://ncbi.nlm.nih.gov/pubmed/20375568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000181014
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