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Stable Fibroblast Growth Factor 2 Dimers with High Pro-Survival and Mitogenic Potential
Fibroblast growth factor 2 (FGF2) is a heparin-binding growth factor with broad mitogenic and cell survival activities. Its effector functions are induced upon the formation of 2:2 FGF2:FGFR1 tetrameric complex. To facilitate receptor activation, and therefore, to improve the FGF2 biological propert...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7312490/ https://ncbi.nlm.nih.gov/pubmed/32526859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114108 |
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