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Lessons on the Sigma-1 Receptor in TNBS-Induced Rat Colitis: Modulation of the UCHL-1, IL-6 Pathway

Inflammatory Bowel Disease (IBD) is an autoimmune ailment of the gastrointestinal (GI) tract, which is characterized by enhanced activation of proinflammatory cytokines. It is suggested that the sigma-1 receptor (σ1R) confers anti-inflammatory effects. As the exact pathogenesis of IBD is still unkno...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Almási, Nikoletta, Török, Szilvia, Dvorácskó, Szabolcs, Tömböly, Csaba, Csonka, Ákos, Baráth, Zoltán, Murlasits, Zsolt, Valkusz, Zsuzsanna, Pósa, Anikó, Varga, Csaba, Kupai, Krisztina
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312485/
https://ncbi.nlm.nih.gov/pubmed/32516975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114046
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