Small cell transformation of non-small cell lung cancer on immune checkpoint inhibitors: uncommon or under-recognized?

BACKGROUND: Histological transformation of oncogene-driven lung adenocarcinoma to small cell lung cancer (SCLC) following treatment with tyrosine kinase inhibitors (TKIs) is a well-described phenomenon. Whether a similar transformation may drive acquired resistance to immune checkpoint inhibitors (I...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Sehgal, Kartik, Varkaris, Andreas, Viray, Hollis, VanderLaan, Paul A, Rangachari, Deepa, Costa, Daniel B
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312456/
https://ncbi.nlm.nih.gov/pubmed/32581048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000697
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