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Scope of 3D Shape-Based Approaches in Predicting the Macromolecular Targets of Structurally Complex Small Molecules Including Natural Products and Macrocyclic Ligands

[Image: see text] A plethora of similarity-based, network-based, machine learning, docking and hybrid approaches for predicting the macromolecular targets of small molecules are available today and recognized as valuable tools for providing guidance in early drug discovery. With the increasing matur...

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Vydáno v:J Chem Inf Model
Hlavní autoři: Chen, Ya, Mathai, Neann, Kirchmair, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312400/
https://ncbi.nlm.nih.gov/pubmed/32368908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c00161
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