Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling

Several clinical reports indicate that the use of amphetaminic anorectic drugs or ergot derivatives could cause valvular heart disease (VHD). We sought to investigate whether valvular lesions develop in response to long-term oral administration of these drugs and to identify drug-targeted biological...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Principais autores: Oury, Cécile, Maréchal, Patrick, Donis, Nathalie, Hulin, Alexia, Hego, Alexandre, Tridetti, Julien, Nguyen, Mai-Linh, Dulgheru, Raluca, Fillet, Marianne, Nchimi, Alain, Lancellotti, Patrizio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312197/
https://ncbi.nlm.nih.gov/pubmed/32503311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114003
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