Developmental loss, but not pharmacological suppression, of renal carbonic anhydrase 2 results in pyelonephritis susceptibility

Carbonic anhydrase II knockout (Car2(−/−)) mice have depleted numbers of renal intercalated cells, which are increasingly recognized to be innate immune effectors. We compared pyelonephritis susceptibility following reciprocal renal transplantations between Car2(−/−) and wild-type mice. We examined...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Ketz, John, Saxena, Vijay, Arregui, Samuel, Jackson, Ashley, Schwartz, George J., Yagisawa, Takafumi, Fairchild, Robert L., Hains, David S., Schwaderer, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311712/
https://ncbi.nlm.nih.gov/pubmed/32390512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00583.2019
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