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Purinergic P2X(1) receptor, purinergic P2X(7) receptor, and angiotensin II type 1 receptor interactions in the regulation of renal afferent arterioles in angiotensin II-dependent hypertension

In ANG II-dependent hypertension, ANG II activates ANG II type 1 receptors (AT(1)Rs), elevating blood pressure and increasing renal afferent arteriolar resistance (AAR). The increased arterial pressure augments interstitial ATP concentrations activating purinergic P2X receptors (P2XRs) also increasi...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Kulthinee, Supaporn, Shao, Weijian, Franco, Martha, Navar, L. Gabriel
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311710/
https://ncbi.nlm.nih.gov/pubmed/32308022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00602.2019
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