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Dietary fructose enhances angiotensin II-stimulated Na(+) transport via activation of PKC-α in renal proximal tubules

Angiotensin II (ANG II) stimulates proximal nephron transport via activation of classical protein kinase C (PKC) isoforms. Acute fructose treatment stimulates PKC and dietary fructose enhances ANG II’s ability to stimulate Na(+) transport, but the mechanisms are unclear. We hypothesized that dietary...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Yang, Nianxin, Hong, Nancy J., Garvin, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311708/
https://ncbi.nlm.nih.gov/pubmed/32390510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2019
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