CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent proangiogenic phenotype

Macrophages play a pivotal role in tissue repair following myocardial infarction (MI). In response to injury, they exist along a spectrum of activation states tightly regulated by their microenvironment. Cardiosphere-derived cells (CDCs) have been shown to mediate cardioprotection via modulation of...

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Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Mentkowski, Kyle I., Mursleen, Asma, Snitzer, Jonathan D., Euscher, Lindsey M., Lang, Jennifer K.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311701/
https://ncbi.nlm.nih.gov/pubmed/32330087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00155.2020
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